Faculty of Natural and Agricultural Sciences
Department of Biochemistry
Birkholtz, L
MSc PhD(Pret) - Associate Professor
NRF Rating: Y2
Contact Details
Research Interests
Research Output
Contact Details:
Telephone number: 012 420 2479
Fax number: 012 362 5302
E-mail address: lynmarie.birkholtz@up.ac.za
Research Interests:
Biochemical and structural characterization of malaria parasite proteins for the development of anti-malarial therapeutics
Bioinformatics and computational biology
Research Output:
Research articles in refereed specialist journals:
Birkholtz L, Williams M, Niemand J, Louw AI, Persson L, Heby O: 2011. Polyamine homoeostasis as a drug target in pathogenic protozoa: peculiarities and possibilities. Biochemical Journal, 438, pp 229-244, Full Text
Verlinden BK, Niemand J, Snyman J, Sharma SK, Beattie RJ, Woster PM, Birkholtz L: 2011. Discovery of novel alkylated(bis)urea and (bis)thiourea polyamine analogues with potent antimalarial activities. Journal of Medicinal Chemistry, 54 (19), pp 6624-6633, Full Text
Williams M, Sprenger J, Human E, Al-Karadaghi S, Persson L, Louw AI, Birkholtz L: 2011. Biochemical characterisation and novel classification of monofunctional S-adenosylmethionine decarboxylase of Plasmodium falciparum. Molecular and Biochemical Parasitology, 180, pp 17-26, Full Text
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