Faculty of Natural and Agricultural Sciences
Department of Biochemistry
Birkholtz, L
MSc PhD(Pret) - Senior Lecturer
NRF Rating: Y2
Contact Details
Research Interests
Research Output
Contact Details:
Telephone number: 012 420 2479
Fax number: 012 362 5302
E-mail address: lynmarie.birkholtz@up.ac.za
Research Interests:
Biochemical and structural characterization of malaria parasite proteins for the development of anti-malarial therapeutics
Bioinformatics and computational biology
Research Output:
Research articles in refereed specialist journals:
Clark K, Niemand J, Reeksting SB, Smit S, Van Brummelen AC, Williams M, Louw AI, Birkholtz L: 2010. Functional consequences of perturbing polyamine metabolism in the malaria parasite, Plasmodium falciparum. Amino Acids, 38 (2), pp 633-644, Full Text
Becker JvW, Mtwisha L, Crampton B, Stoychev S, Van Brummelen AC, Reeksting SB, Louw AI, Birkholtz L, Mancama D: 2010. Plasmodium falciparum Spermidine synthase inhibition results in unique perturbation-specific effects observed on transcript, protein and metabolite levels. BMC Genomics, 11, pp 235-251, Full Text
Smit S, Stoychev S, Louw AI, Birkholtz L: 2010. Proteomic profiling of Plasmodium falciparum through improved, semiquantitative two-dimensional gel electrophoresis. Journal of Proteome Research, 9, pp 2170-2181, Full Text
Niemand J, Birkholtz L, Louw AI, Kirk K: 2010. Polyamine uptake in the malaria parasites, Plasmodium falciparum, is dependent on the parasites membrane potential. Malaria Journal, In Parasite to Prevention: Advances in die understanding of malaria, 9 (2) / Oct, Malaria Journal, p. 25, Full Text
Chapters in books:
Birkholtz L, Burger PB, Aci S, Valadié H, da Costa AL, Brillet L, De Beer TAP, Joubert F, Wells GA, Breton V, Roy S, Louw AI, Marechal E: 2010. In silico Discorvery of chemotherapeutic agents. In Infectious Disease Informatics, (14), SpringerLink, pp 279-304.
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