Faculty of Natural and Agricultural Sciences
School of Biological Sciences
Department of Biochemistry
Louw, AI
MSc(Agric) DSc(Agric)(Pret) - Professor Emeritus
NRF Rating: C2
Contact Details
Research Interests
Research Output
Contact Details:
Telephone number: 012 420 2480
Fax number: 012 362 5302
E-mail address: braam.louw@up.ac.za
Research Interests:
Biochemical and structural characterization of malaria parasite proteins for the development of anti-malarial therapeutics
Bioinformatics and computational biology
Research Output:
Research articles in refereed specialist journals:
Wells GA, Müller IB, Wrenger C, Louw AI: 2009. The activity of Plasmodium falciparum arginase is mediated by a novel inter-monomer salt-bridge between Glu295-Arg404. FEBS Journal, 276, pp 3517-3530.
De Beer TAP, Wells GA, Burger PB, Joubert F, Maréchal E, Birkholtz L, Louw AI: 2009. Antimalarial drug discovery: in silico structural biology and rational drug design. Infectious Disorders-Drug Targets, 9 (3) / 318, p. 304.
Van Brummelen AC, Olszewski KL, Wilinski D, Llinas M, Louw AI, Birkholtz L: 2009. Co-inhibition of Plasmodium falciparum s-adenosylmethionine decarboxylase/ornithine decarboxylase reveals perturbation-specific compensatory mechanisms by transcriptome, proteome and metabolome analyses. Journal of Biological Chemistry, 284 (7) / Feb, pp 4635-4646.
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