Faculty of Health Sciences
School of Medicine
Department of Immunology
Anderson, R
BSc(Hons)(Glasgow) MSc PhD(Witwatersrand) - Professor and Head
Contact Details
Research Interests
Research Output
Contact Details:
Telephone number: 012 319 2425
Fax number: 012 323 0732
E-mail address: ronald.anderson@up.ac.za
Research Interests:
Tuberculosis: Development of novel anti-tuberculosis chemotherapeutic agents
Pharmacological regulation of phagocyte activation in chronic inflammatory disorders
Oxidative stress
HIV-1 mucosal pathogenesis
HIV-1 drug resistance/clinical trials/efficacy of novel antiretrovirals
Investigation of the interactions of pneumolysin with human neutrophils in vitro
Research Output:
Research articles in refereed specialist journals:
Anderson R, Theron AJ, Gravett C, Steel HC, Tintinger G, Feldman C: 2009. Montelukast inhibits neutrophil pro-inflammatory activity by a cyclic AMP-dependent mechanisms. British Journal of Pharmacology, 156, pp 105-115.
Feldman C, Anderson R: 2009. Therapy for pneumococcal bacteremia: Monotherapy or combination therapy?. Current Opinion in Infectious Diseases, 22, pp 137-142.
Cockeran R, Mitchell TJ, Feldman C, Anderson R: 2009. Pneumolysin induces release of matrix metalloproteinase-8 and-9 from human neutrophils. European Respiratory Journal, 34 (5), pp 1167-1170.
Theron AJ, Gravett C, Steel HC, Tintinger GR, Feldman C, Anderson R: 2009. Leukotrines C4 and D4 sensitize human neutrophils for hyperreactivity to chemoattractants. Inflammation Research, 58 (5) / May, pp 263-268.
Steel HC, Theron AJ, Tintinger GR, Anderson R: 2009. Posaconazole attenuates leukotriene B4 release and uptake of calcium by chemoattractant-activated human neutrophils: a potential strategy to control neutrophil-mediated inflammation. Journal of Antimicrobial Chemotherapy, 64 (5) / Nov, pp 1008-1012.
Tintinger GR, Theron AJ, Steel HC, Cockeran R, Pretorius L, Anderson R: 2009. Protein kinase C promotes restoration of calcium homeostasis to platelet activating factor-stimulated human neutrophils by inhibition of phospholipase C. Journal of Inflammation-London, 6 (29), pp Online 1-9, Full Text
Madiga MC, Cockeran R, Mokgotho MP, Anderson R, Mampuru LJ: 2009. Dichloromethane extract of Dicerocaryum senecioides leaves exhibits remarkable anti-inflammatory activity in human T-lymphocytes. Natural Product Research, 23 (11) / Jul, pp 998-1006.
Feldman C, Anderson R: 2009. New insights into pneumococcal disease. Respirology, 14 (2) / Mar, pp 167-179.
Cholo MC, Anderson R, van Rensburg EJ: 2009. Potassium uptake systems of Mycobacterium tuberculosis: Genomic and protein organisation and potential roles in microbial pathogenesis and chemotherapy. Southern African Journal of Epidemiology and Infection, 24 (1), pp 13-16, Full Text
Feldman C, Anderson R: 2009. Non-antimicrobial activity of macrolides: Therapeutic potential in chronic inflammatory airway disorders. Southern African Journal of Epidemiology and Infection, 24 (4), pp 21-26, Full Text
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