Faculty of Health Sciences
School of Medicine
Department of Immunology
Anderson, R
BSc(Hons)(Glasgow) MSc PhD(Witwatersrand) - Professor and Head
Contact Details
Research Interests
Research Output
Contact Details:
Telephone number: 012 319 2425
Fax number: 012 323 0732
E-mail address: ronald.anderson@up.ac.za
Research Interests:
Tuberculosis: Development of novel anti-tuberculosis chemotherapeutic agents
Pharmacological regulation of phagocyte activation in chronic inflammatory disorders
Oxidative stress
HIV-1 mucosal pathogenesis
HIV-1 drug resistance/clinical trials/efficacy of novel antiretrovirals
Investigation of the interactions of pneumolysin with human neutrophils in vitro
Research Output:
Research articles in refereed specialist journals:
Smith LL, McKune AJ, Semple SJ, Sibanda E, Steel HC, Anderson R: 2007. Changes in serum cytokines after repeated bouts of downhill running. Applied Physiology Nutrition And Metabolism-Physiologie Appliquee Nutrition Et Metabolisme, 32, pp 233-240.
Steel HC, Tintinger GR, Theron AJ, Anderson R: 2007. Itraconazole-mediated inhibition of calcium entry into platelet-activating factor-stimulated human neutrophils is due to interference with production of leukotriene B4. Clinical and Experimental Immunology, 150 (1), pp 144-150, Full Text
Feldman C, Anderson R: 2007. Attivitą non antibatterica dei macrolidi. Clinical Drug investigation, 27, pp 27-35.
Uys A, Rapoport BL, Fickl H, Meyer PWA, Anderson R: 2007. Prediction of outcome in cancer patients with febrile neutropenia: comparison of the Multinational Association of Supportive Care in Carcer risk-index score with procalcitonin, C-reactive protein, serum amyloid A, and interleukins-1B, -6, -8 and 10. European Journal of Cancer Care, 16, pp 475-483.
Tintinger GR, Theron AJ, Potjo M, Anderson R: 2007. Reactive oxidants regulate membrane repolariziation and store-operated uptake of calcium by formyl peptide-activated human neutrophils. Free Radical Biology and Medicine, 42, pp 1851-1857, Full Text
Feldman C, Cockeran R, Jedrzejas MJ, Mitchell TJ, Anderson R: 2007. Hyaluronidase augments pneumolysin-mediated injury to human ciliated epithelium. International Journal of Infectious Diseases, 11, pp 11-15, Full Text
Anderson R, Steel HC, Cockeran R, von Gottberg A, de Gouveia L, Klugman KP, Mitchell TJ, Feldman C: 2007. Comparison of the effects of macrolides, amoxicillin, ceftriaxone, doxycycline, tobramycin and flouroquinolones, on the production of pneumolysin by Streptococcus pneumoniae in vitro. Journal of Antimicrobial Chemotherapy, 60 / Sep, pp 1155-1158, Full Text
Anderson R, Steel HC, Cockeran R, Smith AM, von Gottberg A, de Gouveia L, Brink A, Klugman KP, Mitchell TJ, Feldman C: 2007. Clarithromycin alone and in combination with ceftriaxone inhibits the production of pneumolysin by both macrolide-susceptible and macrolide-resistant strains of Streptococcus pneumoniae. Journal of Antimicrobial Chemotherapy, 59, pp 224-229, Full Text
Fickl H, Theron AJ, Anderson R, Mitchell TJ, Feldman C: 2007. Palladium attenuates the pro-inflammatory interactions of C5a, interleukin-8 and pneumolysin with human neutrophils. Journal of Immunotoxicology, 4, pp 247-252.
Feldman C, Anderson R: 2007. A pivotal role for pneumolysin in the immunopathogenesis, treatment and prevention of pneumococcal disease. South African Medical Journal (SAMJ), 97, pp 1141-1145, Full Text
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